Metastats is software for detecting differentially abundant features in metagenomic case/control studies. It is the first tool developed in the context of metagenomic data comprising multiple samples, and relies on a non-parametric t-test.
This software is no longer current, not recommended for use, and is not being provided anymore. Newer tools exist in this space, such as
metagenomeseq,
corncob, and others.